Italy Road Trip Itinerary: 10 Days from Rome to Apulia

Experience Rome, the bustling capital of Italy. This city, rich with exciting history and culture, offers an unparalled mix of ancient explorations and modern living. Immerse yourself in the past and explore the Colosseum, the Roman Forum, and the Vatican. Wander through other must-see destinations like The Spanish Steps, Trevi Fountain, and Pantheon. Experiencing the culinary scene is a delight, from traditional pasta to world-renowned Italian gelati. You can explore daily markets such as Campo de' Fiori for local ingredients and fresh food. A stay in Rome promises great experiences all year round, but it is advisable to take seasonality into account. While spring (April–May) and fall (September–October) offer pleasant weather and less crowds, summer (June–August) has a lively, spirited atmosphere — but can also be hot. No matter when you go, visiting Rome promises an unforgettable journey through the centuries. The unique combination of a rich historical past mixed into a thriving and vibrant modern community makes Italy's Eternal City one of the world's most intriguing and inspiring tourist destinations.

Presided over by the mighty Mount Vesuvius and with the extraordinary archaeological site of Pompeii on its doorstep, the historic Mediterranean city of Naples is steeped in centuries of fascinating history. Founded long before the Italian state—or even the Roman Republic—Naples holds an unparalleled collection of Greek and Roman artifacts. There’s truly no place like it: vast, gritty, and chaotic, yet this modern-day energy plays out against a dramatic backdrop of grand historical piazzas, world-class museums, and stunning Baroque architecture. As the birthplace of pizza and a contender for the richest food scene in a country celebrated for its cuisine, Naples is a paradise for food lovers, offering a dazzling array of local dishes and gourmet experiences.

Located in Italy’s Puglia region, the port city of Bari fringes the Adriatic Sea and is the capital of the area. Bari is the second-largest town in southern Italy and provides convenient transport links to Croatia, Albania, and Greece, while also serving as an excellent stopover for visitors travelling to Brindisi and Lecce. This historic city is an urban hub of contrasts, boasting both a rich history including an array of interesting heritage buildings, as well as a thriving, modern nightlife scene. Meander through the labyrinthine streets of old town Barivecchia, view the impressive 11th-century Basilica di San Nicola and stroll along the Murat quarter’s scenic promenade. Don’t miss the opportunity to sample mouth-watering local Italian cuisine at one of the many traditional trattorias.

Tucked into the eastern edge of the Salento Peninsula, Lecce is a historic jewel of the Apulia region, surrounded by the waters of the Adriatic and Ionian Seas. Known as the “Florence of the South,” Lecce dazzles with Baroque architecture, ancient Roman ruins, and a thriving arts and culture scene. The city's dramatic façades, decorated with quirky gargoyles, twisting columns, and elaborate stonework, are sure to inspire awe. Top attractions include the ornate Church of the Holy Cross, the Roman Amphitheatre, the Duomo, and the fascinating underground Faggiano Museum. Lecce’s charming old town is home to upscale boutiques, cozy cafes, lively bars, and excellent restaurants serving authentic Pugliese fare.