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Southern Italy Itinerary: 6 Days in Rome & Apulia

6 Days

3 Stops

Private transfer

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  1. Destinations
  2. Europe
  3. Italy
  4. Southern Italy Itinerary: 6 Days in Rome & Apulia
From$1,300
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Trip curated by Roman Karin
Expert

My team and I crafted this trip! Want to make it even more your style? Let’s chat — you can book a free planning call with me.

My team and I crafted this trip! Want to make it even more your style? Let’s chat — you can book a free planning call with me.

Recommended route

Customize at any time with an expert

Rome

Day 1 - 2

Experience Rome, the bustling capital of Italy. This city, rich with exciting history and culture, offers an unparalled mix of ancient explorations and modern living. Immerse yourself in the past and explore the Colosseum, the Roman Forum, and the Vatican. Wander through other must-see destinations like The Spanish Steps, Trevi Fountain, and Pantheon. Experiencing the culinary scene is a delight, from traditional pasta to world-renowned Italian gelati. You can explore daily markets such as Campo de' Fiori for local ingredients and fresh food. A stay in Rome promises great experiences all year round, but it is advisable to take seasonality into account. While spring (April–May) and fall (September–October) offer pleasant weather and less crowds, summer (June–August) has a lively, spirited atmosphere — but can also be hot. No matter when you go, visiting Rome promises an unforgettable journey through the centuries. The unique combination of a rich historical past mixed into a thriving and vibrant modern community makes Italy's Eternal City one of the world's most intriguing and inspiring tourist destinations.

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Your accommodation

NH Collection Roma Centro
NH Collection Roma Centro
NH Collection Roma Centro

NH Collection Roma Centro

NH Collection Roma Centro is located in the Prati district, between the Vatican and Castel Sant’Angelo, offering easy access to Rome’s historic landmarks. The rooms are equipped with air conditioning, TVs, and private bathrooms that include a bath, shower, and hairdryer. Guests can enjoy both international and local cuisine at the 324 Lounge Restaurant, which features fresh, locally sourced ingredients. The hotel is close to Piazza del Popolo, Via del Corso, and the shopping area of Via Cola di Rienzo, making it a great base for exploring the city.

Your activity

Vatican & Castel Sant’Angelo Tour

Vatican & Castel Sant’Angelo Tour

Take the tour of the Vatican Museums and Sistine Chapel with no queue at all! No stress to access the Vatican: your professional guide will take you inside and accompany you in a memorable visit to one of the most important art collections worldwide. Admire the numerous halls of the museum, including the spiral staircase, the beautiful Raphael’s rooms and their famous paintings, before entering the Sistine Chapel, Michelangelo’s masterpiece. On your way out from the Sistine Chapel, you will go inside St. Peter’s Basilica through an exclusive access skipping long lines. The tour wouldn’t be complete without a walk in St. Peter’s Square, the open space before the basilica, redesigned by G. L. Bernini, an architectural masterpiece of the Baroque age. Your day continues with a visit of Castel Sant’Angelo, originally built as the tomb of Roman Emperor Hadrian, was later converted into a military fortress, the Pope’s residence, a Renaissance-era prison, and then finally into a museum to preserve the history of Rome. Built in 135 AD, the castle now houses Hadrian’s tomb, Papal apartments, and several magnificent works of art including paintings, sculptures, pottery, frescoes, murals, and more. Choose this tour if you would like to enjoy a professional guided tour to the Vatican Museums, the Sistine Chapel and Castel Sant’Angelo with skip the line access thanks to a special agreement we have. Tour ends at Castel Sant’Angelo area. 

Bari

Day 3 - 4

Located in Italy’s Puglia region, the port city of Bari fringes the Adriatic Sea and is the capital of the area. Bari is the second-largest town in southern Italy and provides convenient transport links to Croatia, Albania, and Greece, while also serving as an excellent stopover for visitors travelling to Brindisi and Lecce. This historic city is an urban hub of contrasts, boasting both a rich history including an array of interesting heritage buildings, as well as a thriving, modern nightlife scene. Meander through the labyrinthine streets of old town Barivecchia, view the impressive 11th-century Basilica di San Nicola and stroll along the Murat quarter’s scenic promenade. Don’t miss the opportunity to sample mouth-watering local Italian cuisine at one of the many traditional trattorias.

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Your accommodation

Hotel Excelsior Bari
Hotel Excelsior Bari
Hotel Excelsior Bari

Hotel Excelsior Bari

Hotel Excelsior Bari offers accommodation located in the heart of the capital of Puglia, Italy. Accommodation options comprise 146 comfortable rooms and suites, each with air conditioning, a hairdryer, a safe, a TV with Sky channels, free Wi-Fi and a direct-dial telephone. Guests can conveniently enjoy meals at the on-site restaurant. Additional amenities include a bar and a gym.

Your activity

Taste your way through Bari

Taste your way through Bari

Experience the vibrant soul of Bari through its flavors on this private street food walking tour through the city’s historic Old Town (Bari Vecchia). Led by a knowledgeable local guide, this tour is a delicious journey into the heart of Puglian cuisine and culture.

As you wind through the city's narrow alleys and lively squares, you'll stop at beloved local spots to sample some of Bari’s most iconic bites:

  • Warm, crusty focaccia barese fresh from the oven
  • Golden panzerotti filled with melted mozzarella and tomato
  • Crispy sgagliozze (fried polenta squares)
  • Crunchy, savory taralli, a true regional favorite

One of the highlights? Watching local women hand-roll orecchiette pasta right outside their homes—an unforgettable glimpse into Bari’s living culinary traditions.

Your tour ends on a sweet note, with a taste of a pasticciotto, a scoop of artisanal gelato, or a sip of limoncello or local wine, depending on what’s in season and available that day.

This is more than just a food tour—it’s a flavorful, authentic experience of Bari’s rich culture and warm hospitality.

Lecce

Day 5 - 6

Tucked into the eastern edge of the Salento Peninsula, Lecce is a historic jewel of the Apulia region, surrounded by the waters of the Adriatic and Ionian Seas. Known as the “Florence of the South,” Lecce dazzles with Baroque architecture, ancient Roman ruins, and a thriving arts and culture scene. The city's dramatic façades, decorated with quirky gargoyles, twisting columns, and elaborate stonework, are sure to inspire awe. Top attractions include the ornate Church of the Holy Cross, the Roman Amphitheatre, the Duomo, and the fascinating underground Faggiano Museum. Lecce’s charming old town is home to upscale boutiques, cozy cafes, lively bars, and excellent restaurants serving authentic Pugliese fare.

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Your accommodation

Hotel Delle Palme
Hotel Delle Palme
Hotel Delle Palme

Hotel Delle Palme

Hotel Delle Palme is located in Lecce, Italy, and is within walking distance from Porta San Biagio and the city centre. The hotel also features a selection of air-conditioned rooms equipped with a safe deposit box, free Wi-Fi, a flat-screen TV, and a private bathroom. The hotel also features a breakfast room located on the ground floor and an on-site restaurant where you can relax and enjoy a delicious meal.

From$1,300
per person
Plan your trip

Accommodations
Transportation
24/7 support
Activities
Tourlane App
Travel plan
Flights

Why plan with an expert?


Roman Karin
Tourlane Expert
Tourlane Expert
Tourlane Expert

200+


Plan with professionals who are explorers themselves.

18+ hours of time saved

Our experts plan and book for you.

8+ Bookings managed

Everything is bundled in one place and perfectly planned.

6+ Transfers coordinated

For optimal transport and comfort.

Excellent

Why plan with an expert?


Roman Karin
Tourlane Expert
Tourlane Expert
Tourlane Expert

200+


Plan with professionals who are explorers themselves.

18+ hours of time saved

Our experts plan and book for you.

8+ Bookings managed

Everything is bundled in one place and perfectly planned.

6+ Transfers coordinated

For optimal transport and comfort.

Excellent

Itinerary inspiration

This six-day journey takes you from the historic streets of Rome to the sun-drenched landscapes of Apulia, showcasing the best of Southern Italy in a short yet immersive experience. Begin with two nights in Rome, where ancient history and modern Italian life intersect. Visit iconic landmarks such as the Vatican and Castel Sant’Angelo, stroll through lively piazzas, and enjoy traditional cuisine in local trattorias while exploring the city at your own pace.

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Midway through your journey, travel south by train to Bari, where coastal charm and southern Italian culture define the experience. From here, continue to Lecce, known for its elegant baroque architecture and warm atmosphere. With seamless transfers and a thoughtfully designed route, this itinerary offers a balanced introduction to Southern Italy, combining historic cities with a relaxed Mediterranean setting.

Day 1–2: Rome (2 Nights)

Begin your journey in Italy’s capital, where history and culture are woven into everyday life.

Your Accommodation

NH Collection Roma Centro

Highlights & Activities

  • Private transfer from the airport to your hotel

  • Guided tour of the Vatican and Castel Sant’Angelo

  • Explore Rome’s historic center and iconic landmarks

  • Enjoy free time for local dining and cultural discoveries

Day 3–4: Bari (2 Nights)

Travel south to Bari, a coastal city with a distinct regional character.

Your Accommodation

Hotel Excelsior Bari

Highlights & Activities

  • Train journey from Rome to Bari

  • Private transfer from the station to your hotel

  • Explore Bari’s historic center and waterfront

  • Discover local cuisine and Adriatic influences

Day 5: Lecce (1 Night)

Continue to Lecce, a city known for its refined architecture and atmosphere.

Your Accommodation

Hotel Delle Palme

Highlights & Activities

  • Train journey from Bari to Lecce

  • Explore Lecce’s baroque architecture and historic streets

  • Experience the city’s relaxed southern Italian ambiance

Day 6: Departure

Your journey concludes in Lecce with a private transfer. Depart with lasting impressions of Southern Italy’s history, culture, and coastal charm.

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Portugal, England & Italy Itinerary: 2 Weeks of Culture and Charm
Portugal, England & Italy Itinerary: 2 Weeks of Culture and Charm
Portugal, England & Italy Itinerary: 2 Weeks of Culture and Charm

Portugal, England & Italy Itinerary: 2 Weeks of Culture and Charm

15 days

5 stops

From $5,500 p.p.

Ein verziertes Gebäude mit farbenfrohen Mosaiken, geschwungenen Balkonen und einzigartigen Fensterformen, das neben traditionelleren Strukturen steht. Grüne Zweige recken sich über die Stadt, und der Himmel ist hell und teilweise bewölkt.
Eine britische königliche Wache in roter Uniform und Bärenfellmütze steht stramm vor einem Wachhäuschen in der Nähe eines Fensters und einer schwarzen Lampe im Buckingham Palace.
Europe Multi-City Itinerary: From Lisbon to London
Europe Multi-City Itinerary: From Lisbon to London
Europe Multi-City Itinerary: From Lisbon to London
Europe Multi-City Itinerary: From Lisbon to London

Europe Multi-City Itinerary: From Lisbon to London

15 days

6 stops

From $5,700 p.p.

Kathedrale von Valencia - ein Muss bei einem Valencia Urlaub
Eine Straße in Faro, Algarve, Portugal
Southern Europe & Edinburgh Itinerary: 21 Days of Culture & Charm
Southern Europe & Edinburgh Itinerary: 21 Days of Culture & Charm
Southern Europe & Edinburgh Itinerary: 21 Days of Culture & Charm
Southern Europe & Edinburgh Itinerary: 21 Days of Culture & Charm

Southern Europe & Edinburgh Itinerary: 21 Days of Culture & Charm

21 days

7 stops

From $6,600 p.p.

Zurich, Fraumunster, Town, City, Urban Skyline
Switzerland & Northern Italy 10-Day Itinerary: Alpine Elegance & Italian Romance
Switzerland & Northern Italy 10-Day Itinerary: Alpine Elegance & Italian Romance
Switzerland & Northern Italy 10-Day Itinerary: Alpine Elegance & Italian Romance
Switzerland & Northern Italy 10-Day Itinerary: Alpine Elegance & Italian Romance
Switzerland & Northern Italy 10-Day Itinerary: Alpine Elegance & Italian Romance

Switzerland & Northern Italy 10-Day Itinerary: Alpine Elegance & Italian Romance

10 days

4 stops

From $7,100 p.p.

Alley im Stadtteil Albaicin in der Altstadt von Granada Andalusien
Seville, Rome, Athens & London: 21-Day Itinerary
Seville, Rome, Athens & London: 21-Day Itinerary
Seville, Rome, Athens & London: 21-Day Itinerary
Seville, Rome, Athens & London: 21-Day Itinerary
Seville, Rome, Athens & London: 21-Day Itinerary

Seville, Rome, Athens & London: 21-Day Itinerary

21 days

6 stops

From $7,100 p.p.

Alpine Crossing Itinerary: Vienna to Milan
Alpine Crossing Itinerary: Vienna to Milan
Alpine Crossing Itinerary: Vienna to Milan
Alpine Crossing Itinerary: Vienna to Milan
Alpine Crossing Itinerary: Vienna to Milan
Alpine Crossing Itinerary: Vienna to Milan

Alpine Crossing Itinerary: Vienna to Milan

14 days

5 stops

From $8,900 p.p.

St. Pierre Cathedral - Geneva, Geneva - Switzerland, Ancient, Architecture, Bell Tower - Tower
14-Day Switzerland & Italy Itinerary: The Alpine-Italian Grand Tour
14-Day Switzerland & Italy Itinerary: The Alpine-Italian Grand Tour
14-Day Switzerland & Italy Itinerary: The Alpine-Italian Grand Tour
14-Day Switzerland & Italy Itinerary: The Alpine-Italian Grand Tour
14-Day Switzerland & Italy Itinerary: The Alpine-Italian Grand Tour

14-Day Switzerland & Italy Itinerary: The Alpine-Italian Grand Tour

15 days

6 stops

From $11,650 p.p.

Tips for your 6 days in Southern Italy

April–June and September–October are the best months. These seasons bring mild weather for exploring Rome’s historic sites, strolling Bari’s old town, and admiring Lecce’s baroque architecture without summer heat.

➔ Best time to travel Italy | Best travel time Apulia

Hotels range from about $55–$90 per night for budget, $90–$180 for mid-range, and $180–$250+ for boutique or luxury. Meals cost $15–$30 in trattorias and $50–$100 in fine dining. Activities include Vatican tours in Rome (~$50–$70) and street food tours in Bari (~$50). Five days typically start around $1,300 per person, depending on style.

➔ Travel cost Italy

Rome offers the Vatican Museums, Sistine Chapel, and Castel Sant’Angelo, alongside lively piazzas and markets. Bari highlights include the Basilica di San Nicola and a private street food tour with orecchiette-making. Lecce’s baroque churches and historic squares bring the journey to a close.

➔ Things to see Italy | Things to see Apulia | Activities Italy

Book Vatican and Castel Sant’Angelo tickets in advance. Travel light for the train ride from Rome to Bari. In Bari, join a guided food walk to discover local culture, and in Lecce, explore on foot to fully enjoy its architecture and atmosphere.

➔ Insider tips Italy

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We would like to thank Alexandra Egertz...

We would like to thank Alexandra Egertz...

R

rosi eckstein

Friendly and competent advice that fulfilled all our wishes. We are looking forward to our upcoming trip to Italy and will get in touch again afterwards to let you know if everything went well.

08/27/2025
As always 😀👍🏻 very satisfied …

As always 😀👍🏻 very satisfied …

C

Carsten

Italy trip …

Italy trip …

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Manuela Schumacher

Manuela Schumacher

Simply perfect

Simply perfect

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Eyvette Thompson

Italy trip

Italy trip

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Caroline Bohrmann

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  • We are once again very satisfied with Tourlane and the collaboration with Ms. Calabrese. She provided me with detailed information and prepared and organized the Italy trip excellently. Happy to book again 😊

    07/11/2025
  • It was a very nice trip and overall we are very satisfied. The Tourlane navigation could be a bit more precise. All the hotels were very good 👍 It was a wonderful time that we would happily repeat again and again.

    06/23/2025
  • We were interested in a round trip through Italy and shortly after our inquiry we already received an appointment for a consultation. The conversation with our Italy expert, Lara Schmidt, was simply great. She not only took all our wishes into account, but also rightly advised against one or two locations because of the weather/season. Shortly afterwards we received our offer (route, hotels, rental car), and what can we say — we got a perfectly arranged trip that really included and even exceeded all our wishes. That’s why we confirmed the trip with Lara directly in the next call and are super excited. @Lara: A BIG THANK YOU for the great exchange — you do this with so much heart and en...

    03/18/2025
  • Lara has organized my IT Trip for summer with my family. She had some many great ideas and provided so much information about the different regions. I´m really looking forward! Thank you Lara :-)

    02/11/2025